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更多關于美國 FDA 21 CFR 第 73 部分的內容，請詳見美國FDA 21 CFR 第73部分關于免除產品證書的食品用著色劑種類匯總
§ 73.500 Saffron.
（a） Identity. （1） The color additive saffron is the dried stigma of Crocus sativus L. The definition of saffron in this paragraph is for the purpose of identity as a color additive only, and shall not be construed as setting forth an official standard for saffron under section 401 of the act.
（2） Color additive mixtures made with saffron may contain as diluents only those substances listed in this subpart as safe and suitable in color additive mixtures for coloring foods.
（b） Uses and restrictions. Saffron may be safely used for the coloring of foods generally, in amounts consistent with good manufacturing practice, except that it may not be used to color foods for which standards of identity have been promulgated under section 401 of the act, unless the use of added color is authorized by such standards.
（c） Labeling. The color additive and any mixtures intended solely or in part for coloring purposes prepared therefrom shall bear, in addition to the other information required by the act, labeling in accordance with the provisions of §70.25 of this chapter.
（d） Exemption from certification. Certification of this color additive is not necessary for the protection of the public health, and therefore batches thereof are exempt from the certification requirements of section 721（c） of the act.
§73.500 藏紅花
（a）特性：
（1）著色劑藏紅花，系藏紅花（Crocus sativus L.）的干燥柱頭。本欄所指的藏紅花，僅指用做著色劑的藏紅色，不同于法規401節中所指具有法定標準的藏紅花。
（2）用藏紅花配制成的食用著色劑混合物，只能選用本分部中所列的安全和適用于食品著色的著色劑混合物稀釋劑。
（b）使用和限制條件：藏紅花在符合現行GMP用量條件下，可安全地用于一般食品的著色，但不得用于本法規§401中所頒布的已確定標準的食品的著色，除非所加入的色素是這類標準所允許的。
（c）標簽標注方式：本著色劑和任何含有本著色劑的混合物，擬單獨使用或起部分著色效果時，除法規所規定的其它所需說明以外，其標簽還應符合本章§70.25中的規定。
（d）免除產品證書：本著色劑免除產品證書以保護公眾健康。所生產的每批產品也免除按法規§721（c）中所規定的需要產品證書。
