2023年7月12日，據歐盟食品安全局（EFSA）消息，應歐盟委員會要求，歐盟動物飼料添加劑和產品（FEEDAP）研究小組就谷氨酸棒桿菌CGMCC 18932發酵生產的L-纈氨酸（L‐valine）作為所有動物飼料添加劑的安全性和有效性發表科學意見。
經過評估，專家小組認為該添加劑對目標物種、消費者和環境是安全的。由于缺乏數據，研究小組無法就該添加劑對皮膚或眼睛產生刺激的可能性得出結論。評估中的添加劑被認為是非反芻動物物種氨基酸L-纈氨酸的有效來源。為了使補充的L-纈氨酸對反芻動物和非反芻動物同樣有效，需要防止其在瘤胃中降解。部分原文報道如下：
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l-valine produced by fermentation using a non-genetically modified strain of Corynebacterium glutamicum (CGMCC 18932). l-Valine is intended to be used in feed and water for drinking as a nutritional additive, functional group amino acids, their salts and analogues, for all animal species and categories. The production strain is considered suitable for the qualified presumption of safety (QPS) approach to safety assessment. The FEEDAP Panel concluded that l-valine produced by C. glutamicum CGMCC 18932 is considered safe for the target species when supplemented to the diet in appropriate amounts according to the nutritional needs of the target species. The use of l-valine produced using C. glutamicum CGMCC 18932 in animal nutrition is considered safe for the consumer and for the environment. No conclusion could be drawn on the potential of l-valine produced using C. glutamicum CGMCC 18932 to be irritant to the skin or eyes, or a dermal sensitiser due to the lack of data. The FEEDAP Panel concluded that the l-valine produced by fermentation using C. glutamicum CGMCC 18932 is an efficacious source of the essential amino acid l-valine for non-ruminant nutrition. To be as efficacious in ruminants as in non-ruminants, supplemental l-valine requires protection against ruminal degradation. The FEEDAP Panel expressed concerns on the use of amino acids in water for drinking for hygienic reasons.
經過評估，專家小組認為該添加劑對目標物種、消費者和環境是安全的。由于缺乏數據，研究小組無法就該添加劑對皮膚或眼睛產生刺激的可能性得出結論。評估中的添加劑被認為是非反芻動物物種氨基酸L-纈氨酸的有效來源。為了使補充的L-纈氨酸對反芻動物和非反芻動物同樣有效，需要防止其在瘤胃中降解。部分原文報道如下：
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of l-valine produced by fermentation using a non-genetically modified strain of Corynebacterium glutamicum (CGMCC 18932). l-Valine is intended to be used in feed and water for drinking as a nutritional additive, functional group amino acids, their salts and analogues, for all animal species and categories. The production strain is considered suitable for the qualified presumption of safety (QPS) approach to safety assessment. The FEEDAP Panel concluded that l-valine produced by C. glutamicum CGMCC 18932 is considered safe for the target species when supplemented to the diet in appropriate amounts according to the nutritional needs of the target species. The use of l-valine produced using C. glutamicum CGMCC 18932 in animal nutrition is considered safe for the consumer and for the environment. No conclusion could be drawn on the potential of l-valine produced using C. glutamicum CGMCC 18932 to be irritant to the skin or eyes, or a dermal sensitiser due to the lack of data. The FEEDAP Panel concluded that the l-valine produced by fermentation using C. glutamicum CGMCC 18932 is an efficacious source of the essential amino acid l-valine for non-ruminant nutrition. To be as efficacious in ruminants as in non-ruminants, supplemental l-valine requires protection against ruminal degradation. The FEEDAP Panel expressed concerns on the use of amino acids in water for drinking for hygienic reasons.
