http://tv.people.com.cn/n/2013/0331/c61600-20978559.html
MassARRAY® DNA質(zhì)譜陣列基因分析系統(tǒng) |
MassARRAY® DNA質(zhì)譜陣列基因分析系統(tǒng)——核酸質(zhì)譜高精度定性定量平臺 MassARRAY® DNA質(zhì)譜陣列基因分析系統(tǒng)是一個(gè)功能強(qiáng)大的核酸質(zhì)譜定性定量平臺，它地結(jié)合了質(zhì)譜檢測的高分辨率、PCR擴(kuò)增的高敏感度，以及生物芯片技術(shù)的高通量，同時(shí)無需雜交及熒光染料等二級標(biāo)記物，直接以分子量為標(biāo)記對樣本進(jìn)行多方位分析。 MassARRAY® DNA質(zhì)譜陣列基因分析系統(tǒng)主要應(yīng)用包含： • 中高通量SNP基因型分析 • GWAS及二代測序驗(yàn)證 • 體細(xì)胞基因突變譜分析 • 基因表達(dá)定量及目標(biāo)基因CNV分析 • DNA甲基化定位定量 • 病原體分子分型 • MassARRAY® DNA質(zhì)譜陣列基因分析系統(tǒng)以其通量高、自動(dòng)化、靈活、結(jié)果準(zhǔn)確、實(shí)驗(yàn)成本低廉等諸多優(yōu)勢成為了大學(xué)、醫(yī)學(xué)生物學(xué)研究所、生物技術(shù)公司、制藥企業(yè)、疾控中心等機(jī)構(gòu)所推崇的研究工具。應(yīng)用領(lǐng)域涵蓋：醫(yī)學(xué)及轉(zhuǎn)化醫(yī)學(xué)、分子生物學(xué)、基因組學(xué)、表觀遺傳學(xué)、農(nóng)業(yè)遺傳育種及轉(zhuǎn)基因技術(shù)等相關(guān)領(lǐng)域。 MassARRAY® Analyzer 4: Setting new standards in speed, performance, and flexibility With its exquisite sensitivity and accuracy, mass spectrometry is ideally suited for the analysis of nucleic acids. The new MassARRAY® Analyzer 4 system brings the power of mass spectrometry, robust molecular biology, and advanced data analysis software to meet the needs of high and low-throughput. It provides increased throughput, faster time-to-results, and the ability to cost-efectively run from tens to thousands of samples – making this an ideal genetic analysis system for use in basic and translational research laboratories. With the new MassARRAY Analyzer 4 system you can: • Conduct rapid, accurate, and cost-efective analyses with a highly sensitive and specifc mass spectrometry-based detection system • Run a variety of applications, from genotyping and somatic mutation analysis to methylation and comparative sequencing • Save research time and maximize efciency with easy-to-use multiplexed assay design and optimization software • Fit experiments into your schedule with fast experimental set-up and rapid data acquisition and analysis • Save money with simple, robust, label-free primer extension Chemistries for detection on the MassARRAY Analyzer 4 system | High Performance | Maximum Flexibility | | Highly accurate MALDI-TOF-based detection provides unparalleled specificity and sensitivity for studies of Genetic variation including somatic mutation detection in heterogeneous samples. The increased chip scan speed coupled with the robust detection system gets you to results faster with minimal system down time. | The MAssARRAY Analyzer 4 system has a small footprint, and is a highly scalable platform with the fexibility to analyze any combination of SNPs and samples for low to high-throughput applications, making it ideally suited for fne mapping studies, and candidate gene analysis downstream of whole genome association studies | | Easy-to-Use | Versatility | | Robust assay design software automates primer design and optimization to maximize efciency and minimize experimental variability. New data acquisition software streamlines your workfow to ensure fast, direct identifcation of genetic targets | The benchtop MassARRAY Analyzer 4 system is ideally suited for targeted genetic analyses across a variety of applications including SNP genotyping, somatic mutation detection, methylation analysis, quantitative gene expression analysis, copy number variation, and comparative sequence analysis. | Comparison of MassARRAY Analyzer 4 system formats | | 96-well | 384-well | | Multiplexing | Up to 36-plex | Up to 36-plex | | Genotypes/day | < 30,000 | Up to 138,000 | | Ideal # of markers | Fewer than 500 | Up to 3,000 | The MassARRAY Analyzer 4 system is ofered in several confgurations to meet your throughput needs. A 384-well system is intended for higher-throughput laboratories with a capacity of up to 138,000 genotypes per day. The 96-well system is specifcally designed to address the needs of low to mid-throughput labs, and is ideally suited for experiments involving fewer than 30,000 genotypes per day (see table). For ordering information please contact your local ofce below. |
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