2024年12月18日，歐盟食品安全局就一種食品酶三酰甘油脂肪酶（triacylglycerol lipase）的安全性評價發布意見。
據了解，這種食品酶是由轉基因米曲霉菌株 NZYM-FL生產的，旨在用于兩種食品生產過程。
經過評估，專家小組得出結論，該食品酶在預期的使用條件下不會引起安全問題。部分原文報道如下：
The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase, EC 3.1.1.3) is produced with the genetically modified Aspergillus oryzae strain NZYM-FL by Novozymes A/S. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that, under the intended conditions of use, this food enzyme did not give rise to safety concerns. Due to the implementation of a new methodology to estimate the dietary exposure to food enzymes in 2016, the European Commission requested EFSA to revise the exposure assessment of this food enzyme by using this new methodology. In this assessment, EFSA realigned the intended uses of this food enzyme to two food manufacturing processes and recalculated the dietary exposure. As the food enzyme-total organic solids (TOS) are removed in one food manufacturing process, the dietary exposure to the food enzyme-TOS was estimated only for the remaining process. It was calculated to be up to 0.492 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (340 mg TOS/kg bw per day, the mid-dose tested), the Panel derived a margin of exposure of at least 691. based on the revised exposure estimate, the margin of exposure calculated thereof and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
據了解，這種食品酶是由轉基因米曲霉菌株 NZYM-FL生產的，旨在用于兩種食品生產過程。
經過評估，專家小組得出結論，該食品酶在預期的使用條件下不會引起安全問題。部分原文報道如下：
The food enzyme triacylglycerol lipase (triacylglycerol acylhydrolase, EC 3.1.1.3) is produced with the genetically modified Aspergillus oryzae strain NZYM-FL by Novozymes A/S. A safety evaluation of this food enzyme was made previously, in which EFSA concluded that, under the intended conditions of use, this food enzyme did not give rise to safety concerns. Due to the implementation of a new methodology to estimate the dietary exposure to food enzymes in 2016, the European Commission requested EFSA to revise the exposure assessment of this food enzyme by using this new methodology. In this assessment, EFSA realigned the intended uses of this food enzyme to two food manufacturing processes and recalculated the dietary exposure. As the food enzyme-total organic solids (TOS) are removed in one food manufacturing process, the dietary exposure to the food enzyme-TOS was estimated only for the remaining process. It was calculated to be up to 0.492 mg TOS/kg body weight (bw) per day in European populations. When combined with the no observed adverse effect level previously reported (340 mg TOS/kg bw per day, the mid-dose tested), the Panel derived a margin of exposure of at least 691. based on the revised exposure estimate, the margin of exposure calculated thereof and the previous evaluation, the Panel concluded that this food enzyme does not give rise to safety concerns under the intended conditions of use.
