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歐盟評估一種L-色氨酸作為添加劑的安全性和有效性

   2020-02-25 食品伙伴網可心781
核心提示:2020年2月24日,據歐盟食品安全局(EFSA)消息,應歐盟委員會要求,歐盟動物飼料添加劑和產品(FEEDAP)研究小組就一種L-色氨酸
  2020年2月24日,據歐盟食品安全局(EFSA)消息,應歐盟委員會要求,歐盟動物飼料添加劑和產品(FEEDAP)研究小組就一種L-色氨酸(L-tryptophan)作為所有動物品種的飼料和飲用水的營養添加劑發表科學意見。
 
  據了解,這種L-色氨酸是由轉基因大腸桿菌菌株CGMCC 7.267發酵產生。經過評估,小組認為,這種添加劑對消費者和環境是安全的。由于缺乏數據,專家小組無法得出添加劑對皮膚和眼睛有刺激性或對皮膚有致敏性的結論。部分原文報道如下:
 
  Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on l‐tryptophan produced by fermentation with a genetically modified strain of Escherichia coli CGMCC 7.267 when used as a nutritional additive in feed and water for drinking for all animal species and categories. The production strain E. coli CGMCC 7.267 is safe for the production of l‐tryptophan. No viable cells or DNA of the production strain were detected in the additive under assessment. The use of l‐tryptophan produced using E. coli CGMCC 7.267 in supplementing feed to compensate for tryptophan deficiency in feedingstuffs is safe for non‐ruminant target species. However, excess doses would create amino acid imbalances with negative consequences on animal performance. The use of unprotected l‐tryptophan in feed poses safety concerns for ruminants. The use of l‐tryptophan produced by fermentation with E. coli CGMCC 7.267 in animal nutrition is considered safe for the consumers and for the environment. The endotoxin activity in the product and its dusting potential indicate an inhalation risk for the user. In the absence of data, the FEEDAP Panel cannot conclude on the potential of the additive to be irritant to skin and eyes or to be a skin sensitiser. The additive l‐tryptophan produced using E. coli CGMCC 7.267 is regarded as an effective source of the amino acid l‐tryptophan. In order to be as efficacious in ruminants as in non‐ruminants, it should be protected from ruminal degradation.
 
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日期:2020-02-25
 
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