2025年4月28日，據歐盟食品安全局（EFSA）消息，應歐盟委員會要求，歐盟動物飼料添加劑和產品（FEEDAP）研究小組就由副地衣芽孢桿菌DSM 33902和枯草芽孢桿菌DSM 33903組成的飼料添加劑對奶牛和其他反芻動物的安全性和有效性發表科學意見。
經過評估，專家小組認為在建議的使用條件下該添加劑對目標物種、消費者和環境是安全的。部分原文報道如下：
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of Bovacillus™, a product containing viable cells of Bacillus paralicheniformis DSM 33902 and Bacillus subtilis DSM 33903, which is intended to be used as a zootechnical additive (functional group: gut flora stabiliser) in the feed of dairy cows and other dairy ruminants. The trade name is Bovacillus™, and it is intended to be commercialised in two formulations: Bovacillus™ 10, to use in feed, and WS, to use in drinking water. B. paralicheniformis and B. subtilis are considered suitable for the qualified presumption of safety (QPS) approach to safety assessment. The identity of the active agents was established, and compliance with the applicable qualifications /confirm/ied. Therefore, Bacillus paralicheniformis DSM 33902 and Bacillus subtilis DSM 33903 are presumed safe for the target species, consumers of products derived from animals fed the additive and the environment. Since no concerns are expected from the other components of the additive, Bovacillus™ is also considered safe for the target species, consumers and the environment. Bovacillus™ 10 and WS are not skin or eye irritants. Due to the nature of the active agents, both forms of the additive are considered respiratory and skin sensitisers. The Panel concludes that Bovacillus™ has the potential to be efficacious as a zootechnical additive when supplemented in the feed of dairy ruminants at 3.8 × 108 CFU/kg complete feed.
經過評估，專家小組認為在建議的使用條件下該添加劑對目標物種、消費者和環境是安全的。部分原文報道如下：
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of Bovacillus™, a product containing viable cells of Bacillus paralicheniformis DSM 33902 and Bacillus subtilis DSM 33903, which is intended to be used as a zootechnical additive (functional group: gut flora stabiliser) in the feed of dairy cows and other dairy ruminants. The trade name is Bovacillus™, and it is intended to be commercialised in two formulations: Bovacillus™ 10, to use in feed, and WS, to use in drinking water. B. paralicheniformis and B. subtilis are considered suitable for the qualified presumption of safety (QPS) approach to safety assessment. The identity of the active agents was established, and compliance with the applicable qualifications /confirm/ied. Therefore, Bacillus paralicheniformis DSM 33902 and Bacillus subtilis DSM 33903 are presumed safe for the target species, consumers of products derived from animals fed the additive and the environment. Since no concerns are expected from the other components of the additive, Bovacillus™ is also considered safe for the target species, consumers and the environment. Bovacillus™ 10 and WS are not skin or eye irritants. Due to the nature of the active agents, both forms of the additive are considered respiratory and skin sensitisers. The Panel concludes that Bovacillus™ has the potential to be efficacious as a zootechnical additive when supplemented in the feed of dairy ruminants at 3.8 × 108 CFU/kg complete feed.
